PKC iota Antikörper (AA 100-300)

Produktnummer ABIN7869853

Der Maus Monoklonal anti-PKC iota Antikörper (Klon PRKCI-4912) (ABIN7869853) detektiert spezifisch PKC iota in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PKC iota Antikörper (AA 100-300) (ABIN7869853)

Target: PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PKC iota Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: PRKCI-4912

Produktdetails anti-PKC iota Antikörper

Bindungsspezifität: AA 100-300

Verwendungszweck: PKC iota Antibody / PRKCI

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 100-300 was used as the immunogen for the PKC iota antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PKC iota antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PKC iota antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PKC iota

Target: PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))

Andere Bezeichnung: PKC iota

Hintergrund: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (, , , l/i, m and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC i 1/2L and are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.

UniProt: P41743

Pathways: Neurotrophin Signalübertragung, Cell-Cell Junction Organization, Tube Formation