SULT1E1 Antikörper (AA 100-294)

Produktnummer ABIN7869810

Der Maus Monoklonal anti-SULT1E1 Antikörper wird verwendet zum Nachweis von SULT1E1 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für SULT1E1 Antikörper (AA 100-294) (ABIN7869810)

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SULT1E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: SULT1E1-7124

Produktdetails anti-SULT1E1 Antikörper

Bindungsspezifität: AA 100-294

Verwendungszweck: Estrogen Sulfotransferase Antibody / SULT1E1 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 100-294) from the human protein was used as the immunogen for the Estrogen Sulfotransferase antibody.

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Estrogen Sulfotransferase antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Estrogen Sulfotransferase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu SULT1E1

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Andere Bezeichnung: Estrogen Sulfotransferase

Hintergrund: The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis