SULT1E1 Antikörper (Middle Region)

Produktnummer ABIN2783458

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-SULT1E1 Antikörper wird verwendet zum Nachweis von SULT1E1 in Proben von Human, Maus, Ratte, Hund, Pferd, Meerschweinchen und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für SULT1E1 Antikörper (Middle Region) (ABIN2783458)

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SULT1E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SULT1E1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: SULT1E1 Antibody - middle region

Sequenz: LMVAGHPNPG SFPEFVEKFM QGQVPYGSWY KHVKSWWEKG KSPRVLFLFY

Homologie: Dog: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against SULT1E1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SULT1E1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48669-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SULT1E1 Antikörper (ABIN2783458)

Yalcin, Kulkarni, Slitt, King: "Bisphenol A sulfonation is impaired in metabolic and liver disease." in: Toxicology and applied pharmacology, Vol. 292, pp. 75-84, (2016) (PubMed).

Yalcin, More, Neira, Lu, Cherrington, Slitt, King: "Downregulation of sulfotransferase expression and activity in diseased human livers." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 9, pp. 1642-50, (2013) (PubMed).

Details zu SULT1E1

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Andere Bezeichnung: SULT1E1

Hintergrund:

Background Information: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.

Gene Name: Sulfotransferase family 1E, estrogen-preferring, member 1

Alternative Symbols: EST, STE, EST-1, ST1E1

Protein Name: Estrogen sulfotransferase

Molekulargewicht: 35

Gen-ID: 6783

NCBI Accession: NP_005411

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis