Phospholipase C delta 3 Antikörper (AA 10-702)

Produktnummer ABIN7869717

Der Kaninchen Polyklonal anti-Phospholipase C delta 3 Antikörper wird verwendet zum Nachweis von Phospholipase C delta 3 in Proben von Human. Er wurde validiert für WB, ELISA, FACS und IF.

Kurzübersicht für Phospholipase C delta 3 Antikörper (AA 10-702) (ABIN7869717)

Target: Phospholipase C delta 3 (PLCd3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase C delta 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-Phospholipase C delta 3 Antikörper

Bindungsspezifität: AA 10-702

Verwendungszweck: PLC-delta-3 Antibody / PLCD3

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R10-Q702) was used as the immunogen for the PLC-delta-3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PLC-delta-3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PLC-delta-3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Phospholipase C delta 3

Target: Phospholipase C delta 3 (PLCd3)

Andere Bezeichnung: PLC-delta-3

Hintergrund: 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 is an enzyme that in humans is encoded by the PLCD3 gene. This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.

UniProt: Q8N3E9

Pathways: WNT Signalweg