Rekombinanter CGRP Antikörper (AA 1-95)

Produktnummer ABIN7869638

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CGRP in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CGRP Antikörper (AA 1-95) (ABIN7869638)

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CGRP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: S100A12-8952R

Produktdetails anti-CGRP Antikörper

Bindungsspezifität: AA 1-95

Verwendungszweck: CGRP Antibody / S100A12

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-95) from the human protein was used as the immunogen for the CGRP antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CGRP antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CGRP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CGRP

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Andere Bezeichnung: CGRP

Hintergrund: The family of EF-hand type Ca2+-binding proteins includes Calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100 Alpha and beta, Calgranulins A (also designated MRP8), B (also designated MRP14) and C (S100A12, CGRP) and the parvalbumin family members, including parvalbumin Alpha and parvalbumin beta (also designated oncomodulin). Calbindin, S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S-100 Alpha and beta are present in a variety of other tissues, and Calbindin is present in intestine and kidney. Parvalbumin Alpha is also found in fast-contracting/relaxing skeletal muscle fibers and parvalbumin beta is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Calgranulin is expressed in macrophages and epithelial cells.

UniProt: P80511

Pathways: Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour