Der Kaninchen Polyklonal anti-IDO2 Antikörper wird verwendet zum Nachweis von IDO2 in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für WB, ELISA, IHC (p) und FACS.
IDO2
Reaktivität: Human
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 750
Applikationshinweise
Optimal dilution of the Indoleamine 2,3-dioxygenase 2 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
After reconstitution, the Indoleamine 2,3-dioxygenase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
IDO2
(Indoleamine 2,3-Dioxygenase 2 (IDO2))
Andere Bezeichnung
Indoleamine 2,3-dioxygenase 2
Hintergrund
IDO2 (Indoleamine 2,3-dioxygenase 2), also called INDOLEAMINE 2,3-DIOXYGENASE-LIKE 1 or INDOL1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the INDOL1 gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan(D-1MT) but not the L-1MT stereoisomer. The Gene Structure of the INDOL1 has 11 exons and spans 74 kb.