GHITM Antikörper (AA 1-345)

Produktnummer ABIN7869226

Der Kaninchen Polyklonal anti-GHITM Antikörper (ABIN7869226) detektiert spezifisch GHITM in ELISA, WB, IF, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GHITM Antikörper (AA 1-345) (ABIN7869226)

Target: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GHITM Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GHITM Antikörper

Bindungsspezifität: AA 1-345

Verwendungszweck: GHITM Antibody / MICS1

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-K345) was used as the immunogen for the GHITM antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the GHITM antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the GHITM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu GHITM

Target: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Andere Bezeichnung: GHITM

Hintergrund: Growth hormone-inducible transmembrane protein (GHITM), also known as transmembrane BAX inhibitor motif containing protein 5 (TMBIM5), is a protein that in humans is encoded by the GHITM gene on chromosome 10. GHITM, also known asMICS1, TMBIM5 or DERP2, is a mitochondrial protein which localizes in the inner membrane. GHITM is involved in mitochondrial morphology in specific cristae structures and the apoptotic release of cytochrome c from the mitochondria. The gene of GHITM maps to chromosome 10q23.1, and encodes a 345-amino-acid protein with a calculated molecular mass of 37 kDa. The apparent molecular weight has been reported to be 42 kDa, the increased size in the protein may be due to post-translational modifications. GHITM can be cleaved into smaller forms of 23-27 kDa.

UniProt: Q9H3K2

Pathways: SARS-CoV-2 Protein Interaktom