CDK12 Antikörper (AA 1-30)

Produktnummer ABIN7869083

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CDK12 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für CDK12 Antikörper (AA 1-30) (ABIN7869083)

Target: CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDK12 Antikörper

Bindungsspezifität: AA 1-30

Verwendungszweck: CrkRS Antibody / CDK12 / Cyclin-dependent kinase 12

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this CrkRS antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the CrkRS antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CrkRS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CDK12

Target: CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))

Andere Bezeichnung: CrkRS

Hintergrund: CrkRS, also known as Cdc2-related kinase, arginine/serine-rich, CDK12 and Cyclin-dependent kinase 12, is a cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. It also regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability.

UniProt: Q9NYV4