HAX1 Antikörper (AA 1-279)

Produktnummer ABIN7869041

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HAX1 in WB, ELISA, IHC (p) und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HAX1 Antikörper (AA 1-279) (ABIN7869041)

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-HAX1 Antikörper

Bindungsspezifität: AA 1-279

Verwendungszweck: HAX1 Antibody / HCLS1-associated protein X-1

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-R279) was used as the immunogen for the HAX1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the HAX1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the HAX1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu HAX1

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Andere Bezeichnung: HAX1

Hintergrund: HCLS1-associated protein X-1 is a protein that in humans is encoded by the HAX1 gene. The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization