Syndecan 1 Antikörper (AA 1-250)

Produktnummer ABIN7868952

Der Maus Monoklonal anti-Syndecan 1 Antikörper wird verwendet zum Nachweis von Syndecan 1 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Syndecan 1 Antikörper (AA 1-250) (ABIN7868952)

Target: Syndecan 1 (SDC1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Syndecan 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: SDC1-7182

Produktdetails anti-Syndecan 1 Antikörper

Bindungsspezifität: AA 1-250

Verwendungszweck: Syndecan-1 Antibody / CD138 / SDC1

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-250) from the human protein was used as the immunogen for the Syndecan-1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Syndecan-1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Syndecan-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Syndecan 1

Target: Syndecan 1 (SDC1)

Andere Bezeichnung: Syndecan-1

Hintergrund: CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinomas.

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism