CDK5 Antikörper (AA 1-226)

Produktnummer ABIN7868863

Der Kaninchen Polyklonal anti-CDK5 Antikörper (ABIN7868863) detektiert spezifisch CDK5 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Zebrafisch (Danio rerio).

Kurzübersicht für CDK5 Antikörper (AA 1-226) (ABIN7868863)

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDK5 Antikörper

Bindungsspezifität: AA 1-226

Verwendungszweck: Zebrafish Cdk5 Antibody

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Cdk5 recombinant protein (amino acids M1-Q226) was used as the immunogen for the Zebrafish Cdk5 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Cdk5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Cdk5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu CDK5

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Andere Bezeichnung: Cdk5

Hintergrund: CDK5, Cyclin-Dependent Kinase 5, is also known as PSSALRE. The p34 (CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle. The PSSALRE expression is in all human tissues and cell lines tested. The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system. To be activated, CDK5 must associate with its regulatory subunit, p35 (CDK5R1). CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.

UniProt: Q9DE44

Pathways: Zellzyklus, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis