CKAP5 Antikörper (AA 1-221)

Produktnummer ABIN7868848

Der Maus Monoklonal anti-CKAP5 Antikörper (ABIN7868848) detektiert spezifisch CKAP5 in WB, IF, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CKAP5 Antikörper (AA 1-221) (ABIN7868848)

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CKAP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-CKAP5 Antikörper

Bindungsspezifität: AA 1-221

Verwendungszweck: CKAP5 Antibody / Ch-TOG

Aufreinigung: Affinity purified

Immunogen: A human recombinant partial protein (amino acids M1-L221) was used as the immunogen for the CKAP5 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CKAP5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CKAP5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu CKAP5

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Andere Bezeichnung: CKAP5

Hintergrund: Cytoskeleton-associated protein 5 is a microtubule-associated protein that in humans is encoded by the CKAP5 gene. It is mapped to 11p11.2. This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation, it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interact ernatively spliced transcript variants encoding different isoforms have been identified.

UniProt: Q14008

Pathways: M Phase