TREM2 Antikörper (AA 1-200)
Kurzübersicht für TREM2 Antikörper (AA 1-200) (ABIN7868778)
Target
Alle TREM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 1-200
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Verwendungszweck
- TREM2 Antibody (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A portion of amino acids 1-200 was used as the immunogen for the TREM2 antibody.
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Isotyp
- IgG
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anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-228) antibody
TREM2 Reaktivität: Ratte WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-100) antibodyTREM2 Reaktivität: Maus, Human, Ratte, Schwein WB, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 22-48), (N-Term) antibodyTREM2 Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB38661 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-227) antibodyTREM2 Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (Internal Region) antibodyVerified TREM2 Reaktivität: Maus ELISA, IF Wirt: Ziege Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 42-56), (Extracellular), (N-Term) antibodyTREM2 Reaktivität: Maus WB, FACS, IHC, LCI Wirt: Kaninchen Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 42-56), (Extracellular), (N-Term) antibody (PE)TREM2 Reaktivität: Maus FACS, LCI Wirt: Kaninchen Polyclonal PE
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) antibody (PE)TREM2 Reaktivität: Maus FACS Wirt: Ratte Monoclonal 78-18 PE
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) antibodyTREM2 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-161) antibodyTREM2 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2B5 unconjugated
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Applikationshinweise
- Optimal dilution of the TREM2 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the TREM2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
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Andere Bezeichnung
- TREM2
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Hintergrund
- Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), known as Nasu-Hakola disease , is a recessively inherited disease where individuals display early-onset progressive dementia and bone cysts, which leads to death. Mutations in TYROBP (DAP12), which codes for a membrane receptor component in natural-killer and myeloid cells and mutations in triggering receptor expressed on myeloid cells-2 (TREM-2), correlate well to the pathology of PLOSL. TREM-2 is a cell surface receptor on human monocyte-derived dendritic cells that forms a receptor signaling complex with DAP12 and triggers activation of the immune response in macrophages and dendritic cells (DC). The TREM-2/DAP12 complex is a molecular promoter of upregulation of CC chemokine receptor 7, partial DC maturation, and DC survival through activation of protein tyrosine kinases and extracellular signal regulated kinase. The human chronic inflammatory TREM-2 gene maps to chromosome 6p21.1 and encodes a 230 amino acid protein.
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UniProt
- Q9NZC2
Target
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