SIGMAR1 Antikörper (AA 1-154)

Produktnummer ABIN7868213

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SIGMAR1 in WB, ELISA und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Affe.

Kurzübersicht für SIGMAR1 Antikörper (AA 1-154) (ABIN7868213)

Target: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIGMAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SIGMAR1 Antikörper

Bindungsspezifität: AA 1-154

Verwendungszweck: Sigma1-receptor Antibody / SIGMAR1

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids G1-H154) was used as the immunogen for the Sigma1-receptor antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Sigma1-receptor antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Sigma1-receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SIGMAR1

Target: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Andere Bezeichnung: Sigma1-receptor

Hintergrund: The sigma-1 receptor, one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the sigma-1 receptor is encoded by the SIGMAR1 gene. This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

UniProt: Q99720

Pathways: SARS-CoV-2 Protein Interaktom