Rekombinanter Podoplanin Antikörper (AA 1-150)

Produktnummer ABIN7868186

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Podoplanin in ELISA, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Podoplanin Antikörper (AA 1-150) (ABIN7868186)

Target: Podoplanin (PDPN)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Podoplanin Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: PDPN-8875R

Produktdetails anti-Podoplanin Antikörper

Bindungsspezifität: AA 1-150

Verwendungszweck: Glycoprotein 36 Antibody / Gp36 / Podoplanin

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-150) from the human protein was used as the immunogen for the Glycoprotein 36 antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Glycoprotein 36 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Glycoprotein 36 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Podoplanin

Target: Podoplanin (PDPN)

Andere Bezeichnung: Glycoprotein 36

Hintergrund: It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN), also called Glycoprotein 36 (Gp36). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport