Rekombinanter FLT3 Antikörper (PE)
Kurzübersicht für Rekombinanter FLT3 Antikörper (PE) (ABIN7867268)
Target
Alle FLT3 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- PE-conjugated Anti-FLT3 antibody(19A5), IgG1 Chimeric mAb
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Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
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Isotyp
- IgG1
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Applikationshinweise
- Flow Cyt 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2°C-8°C for 6 months
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Haltbarkeit
- 6 months
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- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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Andere Bezeichnung
- FLT3
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Hintergrund
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Synonyms: Flt-3,Flk-2,STK-1,CD135,FLK2,FLT-3
Target Background: Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
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UniProt
- P36888
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Pathways
- RTK Signalweg
Target
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