Rekombinanter FGFR4 Antikörper (PE)
Kurzübersicht für Rekombinanter FGFR4 Antikörper (PE) (ABIN7867266)
Target
Alle FGFR4 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- PE-conjugated Anti-FGFR4 antibody(DMC460), IgG1 Chimeric mAb
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Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
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Isotyp
- IgG1
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Applikationshinweise
- Flow Cyt 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2°C-8°C for 6 months
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Haltbarkeit
- 6 months
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- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
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Andere Bezeichnung
- FGFR4
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Hintergrund
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Synonyms: CD334, JTK2, TKF
Target Background: The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]
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UniProt
- P22455
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
Target
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