Rekombinanter CCR1 Antikörper (PE)

Produktnummer ABIN7867198

Der PE-konjugierte Kaninchen Chimeric anti-CCR1 Antikörper (Klon DMC465) (ABIN7867198) detektiert spezifisch CCR1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CCR1 Antikörper (PE) (ABIN7867198)

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CCR1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: DMC465

Produktdetails anti-CCR1 Antikörper (PE)

Verwendungszweck: PE-conjugated Anti-CCR1 antibody(DMC465), IgG1 Chimeric mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C-8°C for 6 months

Haltbarkeit: 6 months

Details zu CCR1

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Andere Bezeichnung: CCR1

Hintergrund:

Synonyms: CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1

Target Background: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]

UniProt: P32246