CD86 Antikörper (PE)
Kurzübersicht für CD86 Antikörper (PE) (ABIN7867187)
Target
Alle CD86 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- PE-conjugated Anti-B7-2 antibody(DM84), Rabbit mAb
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Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
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Isotyp
- IgG
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Applikationshinweise
- Flow Cyt 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2°C-8°C for 6 months
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Haltbarkeit
- 6 months
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- CD86
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Andere Bezeichnung
- B7-2
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Hintergrund
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Synonyms: CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
Target Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
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UniProt
- P42081
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Target
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