Feimin (pThr112) Antikörper

Produktnummer ABIN7866183

Der Maus Monoklonal anti-Feimin Antikörper (ABIN7866183) detektiert spezifisch Feimin in ELISA und SDS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Feimin (pThr112) Antikörper (ABIN7866183)

Target: Feimin

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, SDS-PAGE (SDS)

Produktdetails

Bindungsspezifität: pThr112

Verwendungszweck: Anti-Feimin pT112 (MOUSE) Monoclonal Antibody

Kreuzreaktivität (Details): A BLAST analysis of the sequence of the immunogen shows 100% identity with mouse, human, and bovine. Reactivity against homologues from other sources is not known.

Aufreinigung: Anti-Feimin pT112 Monoclonal Antibody is Protein A purified

Sterilität: Sterile filtered

Immunogen: This phospho monoclonal antibody was prepared in mice after repeated immunizations with a synthetic peptide corresponding to residues surrounding T112 of mouse Feimin protein.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Anti-Feimin pT112 (MOUSE) Antibody has been tested by ELISA. Expect a band approximately 20.1kDa in size corresponding to phosphorylated C5orf24 protein by western blotting in the appropriate cell lysate or extract. Cell lines expressing feimin can be ex

Kommentare:

ELISA Dilution: 1:1:69,000-1:169,000
Western Blot Dilution: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.16 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Antibody is stable for

Haltbarkeit: 12 months

Antigendetails

Target: Feimin

Hintergrund: Background: The Feimin protein, also known as UPF0461 protein or C5orf24, involves regulatory roles within the cell and its exact role is under investigation. Feimin is a newly discovered myokine that complements insulin by fine-tuning glucose levels and boosting exercise capacity, especially under conditions where insulin is less effective. Highly conserved Feimin functions in both glucose homeostasis and has a direct role in muscle thermogenesis. Feimin can be secreted by muscle and act as a myokine where it can affect tissues by engaging MERTK receptor thereby activating AKT. Cellular Feimin (cFeimin) functions as a transcription regulator by interacting with FOXC2 protein, where it helps to enhance exercise performance by reducing thermogenesis.
Synonyms: Chromosome 5 Open Reading Frame 24, UPF0461 Protein C5orf24, FLJ37562, Feimin

Gen-ID: 134553

NCBI Accession: NP_001129058.1

UniProt: Q80X32