IL-10 Antikörper

Produktnummer ABIN7866177

Der Ratte Monoklonal anti-IL-10 Antikörper (Klon R-625) (ABIN7866177) detektiert spezifisch IL-10 in FACS und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL-10 Antikörper (ABIN7866177)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-10 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: R-625

Produktdetails anti-IL-10 Antikörper

Verwendungszweck: Rat anti Human IL-10

Produktmerkmale: IL-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. It defects in IL10 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease.

Aufreinigung: Protein A/G Chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Details zu IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Andere Bezeichnung: IL-10

Hintergrund: Rat anti human Interleukin-4, IL-4, unconjugated

UniProt: P22301

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints