Thyroglobulin Antikörper

Produktnummer ABIN7865744

Dieser Maus Monoklonal Antikörper detektiert spezifisch Thyroglobulin in IHC, WB, ELISA, FACS, ICC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Thyroglobulin Antikörper (ABIN7865744)

Target: Thyroglobulin (TG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Thyroglobulin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: EBS-O-170

Produktdetails anti-Thyroglobulin Antikörper

Verwendungszweck: anti-Thyroglobulin mouse monoclonal, EBS-O-170, purified

Aufreinigung: affinity chromatography

Immunogen: human thyroglobulin

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)

FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)

WB_dilution: 1:100-1:200 (0.5-1 μg/mL)

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

elisa_dilution: assay dependent

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: store at 2 - 8 °C

Details zu Thyroglobulin

Target: Thyroglobulin (TG)

Andere Bezeichnung: Thyroglobulin

Hintergrund: EBS-O-170 reacts with thyroglobulin, a 660 kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. The vast majority of follicular carcinomas of the thyroid are positive for thyroglobulin even though sometimes only focally. Poorly differentiated thyroid carcinomas are frequently thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. EBS-O-170 has a high affinity for thyroglobulin (Ka = 8.6 x 10^-9). Positive control: Human thyroid.

Pathways: Thyroid Hormone Synthesis