SALL4 Antikörper
Kurzübersicht für SALL4 Antikörper (ABIN7865730)
Target
Alle SALL4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- anti-SALL4 mouse monoclonal, IHC659, purified
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Aufreinigung
- affinity chromatography
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Immunogen
- Recombinant Human SALL4
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Isotyp
- IgG1
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Applikationshinweise
- Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- store at 2 - 8 °C
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- SALL4 (Sal-Like 4 (SALL4))
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Andere Bezeichnung
- SALL4
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Hintergrund
- Sal-Like Protein 4 (SALL4) is a zinc finger transcription factor found in germ cells and human blood progenitor cells, with functional involvement in modulating Oct-4 to maintain embryonic stem cell pluripotency. SALL4 is a useful marker for acute myeloid leukemia, B-cell acute lymphocytic leukemia, intratubular germ cell neoplasia, seminomas/dysgerminomas, and yolk sac tumours (both pediatric and postpubertal). Anti-SALL4 is used to detect embryonal carcinomas, hepatocellular carcinoma (HCC), gliomas, ovarian primitive germcell tumours, choriocarcinomas, spermatogonia, teratoma, gastric cancer, breast cancer, and lung cancer. Expression of SALL4 is often associated with poor prognosis in HCC, and with metastasis in endometrial cancer, colorectal carcinoma, and esophageal squamous cell carcinoma.
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Pathways
- Stem Cell Maintenance, Tube Formation
Target
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