PAX5 Antikörper

Produktnummer ABIN7865710

Der Maus Monoklonal anti-PAX5 Antikörper (Klon IHC005) (ABIN7865710) detektiert spezifisch PAX5 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PAX5 Antikörper (ABIN7865710)

Target: PAX5 (Paired Box 5 (PAX5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAX5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: IHC005

Produktdetails anti-PAX5 Antikörper

Verwendungszweck: anti-PAX-5 mouse monoclonal, IHC005, purified

Aufreinigung: affinity chromatography

Immunogen: Recombinant Human PAX-5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: store at 2 - 8 °C

Details zu PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Andere Bezeichnung: PAX-5

Hintergrund: PAX5 is a member of the paired box (PAX) family of transcription factors, which are key regulators in early development. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP), whose expression is limited to early stages of B-cell differentiation. Anti-PAX5 is useful in differentiating between classic Hodgkin's lymphoma versus multiple myeloma and solitary plasmacytoma, as the protein is expressed in mature and precursor B-cell non-Hodgkin's lymphomas/leukemias while being absent from the other two conditions. Diffuse large B-cell lymphomas are positive for PAX5, with the exception of those with terminal B-cell differentiation, and T-cell neoplasms do not stain with Anti-PAX5.