IFNA2 Antikörper

Produktnummer ABIN7865671

Der Maus Monoklonal anti-IFNA2 Antikörper (Klon N27) (ABIN7865671) detektiert spezifisch IFNA2 in ELISA, WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IFNA2 Antikörper (ABIN7865671)

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Klon: N27

Produktdetails anti-IFNA2 Antikörper

Verwendungszweck: anti-Interferon α 2 mouse monoclonal, N27, purified

Aufreinigung: affinity chromatography

Immunogen: E.coli derived recombinant human IFNalpha2c

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

WB_dilution: 1:50-1:100 (1-2 μg/mL)

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

elisa_dilution: assay dependent

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: store at 2 - 8 °C

Details zu IFNA2

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Andere Bezeichnung: Interferon alpha 2

Hintergrund: The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNα family has over 20 genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNα are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNα include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNα are now known and seem to be expressed on most cell types. N27 is specific for human IFNα2 and does not cross react with human IFNα1. N27 reacts with linear peptide 43aa-53aa, placing the epitope outside the immunodominant regions I and II. Positive control: Human IFNα2, Namalwa and KGI cells. Pair: N39

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C