IFNA1 Antikörper

Produktnummer ABIN7865669

Dieser Maus Monoklonal Antikörper detektiert spezifisch IFNA1 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IFNA1 Antikörper (ABIN7865669)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: Feb-48

Produktdetails anti-IFNA1 Antikörper

Verwendungszweck: anti-Interferon α 1 mouse monoclonal, 2-48, purified

Aufreinigung: affinity chromatography

Immunogen: E.coli derived recombinant human interferon alpha 1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

WB_dilution: 1:50-1:100 (1-2 μg/mL)

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

elisa_dilution: assay dependent

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: store at 2 - 8 °C

Details zu IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Andere Bezeichnung: Interferon alpha 1

Hintergrund: The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNα family has over 20 genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNα are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNα include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNα are now known and seem to be expressed on most cell types. 2-48 Is specific for human interferon α 1 and does not cross react with human interferon α 2. Positive control: Human interferon α 1.

Pathways: JAK-STAT Signalweg, Hepatitis C