CD33 Antikörper
Kurzübersicht für CD33 Antikörper (ABIN7865586)
Target
Alle CD33 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- anti-CD33 / SIGLEC3 mouse monoclonal, 33-20, purified
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Aufreinigung
- affinity chromatography
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Immunogen
- stimulated human AML cells
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Isotyp
- IgG1 kappa
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anti-CD33 (CD33) (AA 101-200) antibody
CD33 Reaktivität: Human, Maus FACS, WB, ELISA, IHC (fro), ICC, IF (p), IF (cc), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 15-237) antibodyCD33 Reaktivität: Human FACS, WB, IHC, ELISA Wirt: Maus Monoclonal 2C6B7 unconjugated
anti-CD33 (CD33) (AA 15-237) antibodyCD33 Reaktivität: Human FACS, IHC, ELISA Wirt: Maus Monoclonal 2C6B7 unconjugated
anti-CD33 (CD33) (AA 18-240) antibodyCD33 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 49-259) antibodyCD33 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 1-364) antibodyCD33 Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 2D12-G4 unconjugated
anti-CD33 (CD33) (AA 261-364) antibodyCD33 Reaktivität: Human FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 18-259) antibodyCD33 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) antibodyCD33 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 18-269) antibodyCD33 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM77 unconjugated
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Applikationshinweise
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ICC/IF_dilution: 1:50-1:100 (1-2 μg/mL)
FACS_dilution: 1-2 μg/million cells
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100 μg/mL
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Buffer
- PBS with 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- store at 2 - 8 °C
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- CD33
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Andere Bezeichnung
- CD33 / SIGLEC3
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Hintergrund
- CD33 is a 67 kDa glycoprotein of the sialic acid-binding immunoglobulin-like lectin (SIGLEC) family, displaying the immune-receptor tyrosine-based inhibitory motif (ITIM), able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies. ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic linage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells. Positive control: Human dendritic and mast cells. Human lymph node and tonsil.
Target
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