beta-2 Microglobulin Antikörper
Kurzübersicht für beta-2 Microglobulin Antikörper (ABIN7865565)
Target
Alle beta-2 Microglobulin (B2M) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- anti-Beta-2-microglobulin mouse monoclonal, EBS-O-109, purified
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Kreuzreaktivität (Details)
- not with non human primates
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Aufreinigung
- affinity chromatography
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Immunogen
- human PBL from a T-ALL patient
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Isotyp
- IgG2a kappa
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Applikationshinweise
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FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
elisa_dilution: assay dependent
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100 μg/mL
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Buffer
- PBS with 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- store at 2 - 8 °C
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Andere Bezeichnung
- Beta-2-microglobulin
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Hintergrund
- EBS-O-109 reacts with human β-2 microglobulin, a 22 kDa protein, which associates non-covalently with the 44 kDa α1-chain of the HLA Class I complex found on all nucleated cells and on platelets. There is no reaction with erythrocytes, neither with non-human primate cells. The detection of β-2 microglobulin in body fluids has been used as a tumor marker, renal failure marker and for monitoring patients with HIV infection. Positive control: Human PBL.
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Pathways
- T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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