MRPL41 Antikörper (AA 210-290)

Produktnummer ABIN7862460

Der Kaninchen Polyklonal anti-MRPL41 Antikörper wird verwendet zum Nachweis von MRPL41 in Proben von Human. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für MRPL41 Antikörper (AA 210-290) (ABIN7862460)

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL41 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MRPL41 Antikörper

Bindungsspezifität: AA 210-290

Verwendungszweck: Rabbit Anti-PIG3 Polyclonal Antibody

Spezifität: PIG3 Polyclonal Antibody detects endogenous levels of PIG3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human PIG3 at AA range: 210-290

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MRPL41

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Andere Bezeichnung: PIG3

Hintergrund: TP53I3, PIG3, Quinone oxidoreductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 proteinTumor protein p53 inducible protein 3 encoded by TP53I3 is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. TP53I3 is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate TP53I3 by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for TP53I3.

Molekulargewicht: 36kD

Gen-ID: 9540

UniProt: Q53FA7

Pathways: p53 Signalweg