MRPL41 Antikörper (C-Term)

Produktnummer ABIN1536787

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MRPL41 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MRPL41 Antikörper (C-Term) (ABIN1536787)

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL41 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB30609

Produktdetails anti-MRPL41 Antikörper

Bindungsspezifität: AA 174-203, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PIG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the C-terminal region of human PIG3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PIG3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu MRPL41

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Andere Bezeichnung: PIG3

Hintergrund: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.

Molekulargewicht: 35536

Gen-ID: 9540

NCBI Accession: NP_001193731, NP_004872, NP_671713

UniProt: Q53FA7

Pathways: p53 Signalweg