Rekombinanter CEA Antikörper

Produktnummer ABIN7865504

Der Kaninchen Monoklonal anti-CEA Antikörper (Klon MSVA-465R) (ABIN7865504) detektiert spezifisch CEA in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CEA Antikörper (ABIN7865504)

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CEA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: MSVA-465R

Produktdetails anti-CEA Antikörper

Expressionssystem: HEK-293 Cells

Verwendungszweck: Recombinant Carcinoembryonic Antigen (CEA) / CD66 Antibody

Spezifität: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Aufreinigung: Ab produced in HEK293 cell mammalian-based expression system.

Immunogen: Recombinant full-length human CEA protein

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. ,Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CEA

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Andere Bezeichnung: Carcinoembryonic Antigen

Hintergrund:

Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1)

Colon: An at least moderate cytoplasmic CEA staining should be seen in the vast majority of columnar epithelial cells.

Molekulargewicht: 80-200kDa

Gen-ID: 1048, 709196

UniProt: P06731