Rekombinanter Cytokeratin 7 Antikörper (AA 1-100)

Produktnummer ABIN7865508

Der Kaninchen Monoklonal anti-Cytokeratin 7 Antikörper wird verwendet zum Nachweis von Cytokeratin 7 in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter Cytokeratin 7 Antikörper (AA 1-100) (ABIN7865508)

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: KRT7-13672R

Produktdetails anti-Cytokeratin 7 Antikörper

Bindungsspezifität: AA 1-100

Expressionssystem: HEK-293 Cells

Verwendungszweck: Recombinant Cytokeratin 7 (Glandular and Transitional Epithelial Marker) Antibody

Spezifität: Cytokeratin 7 in humans is a protein encoded by the KRT7 gene. It is always as a keratin pair with Cytokeratin 19. Cytokeratin 7 is expressed on most ductal and glandular epithelium including lung, breast, bladder and female genital tract, but not in most gastrointestinal epithelium, prostate, hepatocyte and squamous epithelium. In tumor tissues, its expression is absent in colon cancer, prostate cancer and squamous carcinomas. Cytokeratin 7 is often used in concert with Cytokeratin 20 and CDX-2 to aid in distinguishing ovarian, pulmonary and breast carcinomas (CK7+) from colon carcinomas (CK7-).

Aufreinigung: Ab produced in HEK293 cell mammalian-based expression system.

Immunogen: Recombinant fragment (around aa1-100) of human KRT7 protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Cytokeratin 7

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Andere Bezeichnung: Cytokeratin 7

Hintergrund:

CK-7, K2C7, Keratin 55K Type II Cytoskeletal, Keratin Simple Epithelial Type 1 K7, Keratin Type II Cytoskeletal 7, Krt2-7, KRT7, Sarcolectin, SCL, Type II Mesothelial Keratin K7, Type-II Keratin Kb7

Pancreas: CK7 staining is at least weak to moderate cytoplasmic intercalating ducts and strong in large pancreatic ducts, SK-BR-3. HeLa.

Molekulargewicht: 55kDa

Gen-ID: 3855, 411501

UniProt: P08729