YY1 Antikörper

Produktnummer ABIN7863950

Dieser Maus Monoklonal Antikörper detektiert spezifisch YY1 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für YY1 Antikörper (ABIN7863950)

Target: YY1 (YY1 Transcription Factor (YY1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser YY1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: YY1-5436

Produktdetails anti-YY1 Antikörper

Verwendungszweck: YY1 (Transcription Factor) Antibody

Spezifität: The YY1 transcription factor, also known as NF-E1 (human) and Delta or UCRBP (mouse) is of interest due to its diverse effects on a wide variety of target genes. YY1 is broadly expressed in a wide range of cell types and contains four C-terminal zinc finger motifs of the Cys-Cys-His-His type and an unusual set of structural motifs at its N-terminal end. It binds to downstream elements in several vertebrate ribosomal protein genes, where it apparently acts positively to stimulate transcription and can act either negatively or positively in the context of the immunoglobulin k 3' enhancer and immunoglobulin heavy-chain 79oΩE1 site as well as the P5 promoter of the adenoassociated virus. It thus appears that YY1 is a bifunctional protein, capable of functioning as an activator in some transcriptional control elements and a repressor in others.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: His-tagged YY1 protein

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu YY1

Target: YY1 (YY1 Transcription Factor (YY1))

Andere Bezeichnung: YY1

Hintergrund:

CF1, Delta transcription factor, INO80 complex subunit S, NF E1, NFE1, Transcriptional repressor protein YY1, UCR motif DNA binding protein, UCRBP, Yin and yang 1, Yin and Yang 1 protein, YY-1, YY1 transcription factor

Human kidney|tonsil or cervix carcinoma tissues

Molekulargewicht: 40/68kDa

Gen-ID: 7528, 388927

UniProt: P25490