Rekombinanter Ubiquitin Antikörper

Produktnummer ABIN7862249

Dieser Maus Monoklonal Antikörper detektiert spezifisch Ubiquitin in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Ubiquitin Antikörper (ABIN7862249)

Target: Ubiquitin (Ub)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ubiquitin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: RFPM1

Produktdetails anti-Ubiquitin Antikörper

Verwendungszweck: Recombinant Ubiquitin (Autophagy Marker) Antibody

Spezifität: Ubiquitin, a small protein consisting of 76 amino acids, has been found in all eukaryotic cells studied. It is one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation, which eliminates most intracellular defective proteins as well as normal proteins with a rapid turnover. Degradation involves covalent binding of ubiquitin to the protein to be degraded and it is believed that in this way ubiquitin acts to label the protein for disposal by intracellular proteases. The most abundant ubiquitin-protein conjugate, however, is ubiquitin-histone H2A. This conjugate is not degraded. Since such ubiquitinated histones are present primarily in actively transcribed chromosomal regions, ubiquitin may play a role in regulation of gene expression.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Ubiquitin conjugated with glutaraldehyde crosslinked to keyhole limpet hemocyanin (KLH).

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Ubiquitin

Target: Ubiquitin (Ub)

Andere Bezeichnung: Ubiquitin

Hintergrund:

Epididymis secretory protein Li 50, Polyubiquitin B, RPS27A, UBA52, UBA80, UBB, UBC, UBCEP1, UBCEP2, Ubiquitin, Ubiquitin B

HeLa or Raji cells. Human brain.

Molekulargewicht: 9kDa

Gen-ID: 7314, 356190, 520348

UniProt: P0CG47

Pathways: Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway