TNC Antikörper

Produktnummer ABIN7864781

Der Maus Monoklonal anti-TNC Antikörper (Klon TNC-4805) (ABIN7864781) detektiert spezifisch TNC in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TNC Antikörper (ABIN7864781)

Target: TNC (Tenascin C (TNC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNC Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: TNC-4805

Produktdetails anti-TNC Antikörper

Verwendungszweck: Tenascin C (Stromal Marker for Epithelial Malignancy) Antibody

Spezifität: In Western blotting, it reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked 79oΩhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human full-length TNC protein

Isotyp: IgG2c, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu TNC

Target: TNC (Tenascin C (TNC))

Andere Bezeichnung: Tenascin C

Hintergrund:

Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion (HXB), JI, Myotendinous antigen, Neuronectin, TNC

and lung carcinomas. Staining of normal fibroblasts serves as internal positive control (IHC).|Extracellular matrix in tonsil and blood vessels. Stroma of many tumors such as breast|squamous cell

Molekulargewicht: 210kDa and 300kDa

Gen-ID: 3371, 143250

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development