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TNC Antikörper

TNC Reaktivität: Human IHC, IF, FACS, StM Wirt: Maus Monoclonal SPM319 unconjugated
Produktnummer ABIN6939675
  • Target Alle TNC Antikörper anzeigen
    TNC (Tenascin C (TNC))
    Reaktivität
    • 78
    • 43
    • 37
    • 15
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 70
    • 30
    • 2
    • 2
    • 1
    Maus
    Klonalität
    • 64
    • 41
    Monoklonal
    Konjugat
    • 47
    • 11
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TNC Antikörper ist unkonjugiert
    Applikation
    • 73
    • 26
    • 26
    • 25
    • 23
    • 17
    • 13
    • 11
    • 11
    • 10
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    Spezifität
    In Western blotting, it reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
    Keine Kreuzreaktivität
    Ratte (Rattus)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Human breast carcinoma
    Klon
    SPM319
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product TNC Primärantikörper
  • Applikationshinweise

    Positive Control: Extracellular matrix in tonsil and blood vessels. Stroma of many tumors such as breast, squamous cell and lung carcinomas. Staining of normal fibroblasts serves as internal positive control.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), ,Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) ,Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    TNC (Tenascin C (TNC))
    Andere Bezeichnung
    TNC (TNC Produkte)
    Synonyme
    tn antikoerper, 150-225 antikoerper, GMEM antikoerper, GP antikoerper, HXB antikoerper, JI antikoerper, TN antikoerper, TN-C antikoerper, AI528729 antikoerper, C130033P17Rik antikoerper, Hxb antikoerper, Ten antikoerper, cytotactin antikoerper, tenascin-C antikoerper, P230 antikoerper, tenc antikoerper, wu:fk04d02 antikoerper, tenascin C L homeolog antikoerper, tenascin C antikoerper, tnc.L antikoerper, TNC antikoerper, MCYG_00667 antikoerper, tnc antikoerper, Tnc antikoerper
    Molekulargewicht
    210kDa and 300kDa
    Gen-ID
    3371
    UniProt
    P24821
    Pathways
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
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