Rekombinanter RPSA/Laminin Receptor Antikörper

Produktnummer ABIN7863079

Der Maus Monoklonal anti-RPSA/Laminin Receptor Antikörper wird verwendet zum Nachweis von RPSA/Laminin Receptor in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter RPSA/Laminin Receptor Antikörper (ABIN7863079)

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RPSA/Laminin Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: RRPSA-6333

Produktdetails anti-RPSA/Laminin Receptor Antikörper

Verwendungszweck: Recombinant Laminin Receptor/ RPSA (Marker of Metastatic Potential) Antibody

Spezifität: Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human RPSA protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu RPSA/Laminin Receptor

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Andere Bezeichnung: Laminin Receptor

Hintergrund:

34/67 kDa Laminin Receptor, 37 kDa Laminin Receptor precursor, 37/67 kDa Laminin Receptor, 37LRP, 40S Ribosomal Protein SA, 67 kDa Laminin Receptor, 67LR, Colon Carcinoma Laminin-binding Protein, LAMBR, Laminin receptor 1, Laminin-binding Protein precursor p40, LAMR1, LBP/p40, LRP/LR, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, Ribosomal Protein SA (RPSA)

colon or ovarian carcinoma., MCF-7, MDA-MB-453or HEK293 cells.Human breast

Molekulargewicht: 37-67kDa

Gen-ID: 3921, 449909

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly