NOC4L Antikörper

Produktnummer ABIN7863519

Der Maus Monoklonal anti-NOC4L Antikörper wird verwendet zum Nachweis von NOC4L in Proben von Human. Er wurde validiert für FACS und IF.

Kurzübersicht für NOC4L Antikörper (ABIN7863519)

Target: NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NOC4L Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: PCRP-NOC4L-1B2

Produktdetails anti-NOC4L Antikörper

Verwendungszweck: Nucleolar complex-associated protein 4-like protein (NOC4L) Antibody

Spezifität: Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human NOC4L protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu NOC4L

Target: NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

Andere Bezeichnung: Nucleolar complex-associated protein 4-like protein

Hintergrund:

NOC4 protein homolog, NOC4-like protein, Nucleolar complex protein 4 homolog, Nucleolar complex-associated protein 4-like protein

HeLa or 293T cells.

Molekulargewicht: 58.4kDa

Gen-ID: 79050, 558536

UniProt: Q9BVI4