LEF1 Antikörper
Kurzübersicht für LEF1 Antikörper (ABIN7861647)
Target
Alle LEF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- LEF1 / TCF1 alpha (Transcription Factor) Antibody
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Spezifität
- Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment of human LEF1 protein (exact sequence is proprietary)
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide store at 2 to 8°C. Antibody without azide store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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Andere Bezeichnung
- LEF1
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Hintergrund
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Lymphoid enhancer-binding factor 1 (LEF1), T cell specific transcription factor 1 alpha (TCF1a), TCF1 alpha, TCF10, TCF7L3, Transcription factor T cell specific 1 alpha
Human tonsil and thymus. K-562, T98G
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Molekulargewicht
- 44kDa
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Gen-ID
- 51176, 726506
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UniProt
- Q9UJU2
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Pathways
- WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
Target
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