GTF2IRD2 Antikörper

Produktnummer ABIN7861390

Der Maus Monoklonal anti-GTF2IRD2 Antikörper (Klon PCRP-GTF2IRD2-1B4) (ABIN7861390) detektiert spezifisch GTF2IRD2 in WB und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GTF2IRD2 Antikörper (ABIN7861390)

Target: GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GTF2IRD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: PCRP-GTF2IRD2-1B4

Produktdetails anti-GTF2IRD2 Antikörper

Verwendungszweck: GTF2IRD2 Antibody

Spezifität: The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (GTF2I repeat domain containing 2) and GTF2IRD2B (general transcription factor II-I repeat domain-containing protein 2B). Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human GTF2IRD2 protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu GTF2IRD2

Target: GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))

Andere Bezeichnung: GTF2IRD2

Hintergrund:

FP630, GTF2IRD2A, GTF2IRD2 alpha

HeLa or K562 cells.

Molekulargewicht: 107kDa

Gen-ID: 84163, 647039

UniProt: Q86UP8