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GTF2IRD2 Antikörper

GTF2IRD2 Reaktivität: Human WB, FACS Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN7127094
  • Target Alle GTF2IRD2 Antikörper anzeigen
    GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))
    Reaktivität
    • 19
    • 1
    • 1
    Human
    Wirt
    • 16
    • 3
    Maus
    Klonalität
    • 18
    • 1
    Monoklonal
    Konjugat
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser GTF2IRD2 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 14
    • 12
    • 2
    Western Blotting (WB), Flow Cytometry (FACS)
    Spezifität
    The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (GTF2I repeat domain containing 2) and GTF2IRD2B (general transcription factor II-I repeat domain-containing protein 2B). Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human GTF2IRD2 protein
    Isotyp
    IgG2b
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  • Applikationshinweise

    Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or K562 cells.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))
    Andere Bezeichnung
    GTF2IRD2 (GTF2IRD2 Produkte)
    Synonyme
    FP630 antikoerper, GTF2IRD2 alpha antikoerper, GTF2IRD2A antikoerper, 1700012P16Rik antikoerper, GTF2I repeat domain containing 2 antikoerper, GTF2IRD2 antikoerper, Gtf2ird2 antikoerper
    Hintergrund
    FP630, GTF2IRD2A, GTF2IRD2 alpha,GTF2IRD2
    Cellular localisation: Nucleus.
    Molekulargewicht
    107kDa
    Gen-ID
    84163, 647039
    UniProt
    Q86UP8
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