GCLM Antikörper
Kurzübersicht für GCLM Antikörper (ABIN7861362)
Target
Alle GCLM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- GCLM (DNA Mismatch Repair Protein) Antibody
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Spezifität
- G-glutamylcysteine synthetase (g-GCS) is the rate limiting enzyme for glutathione (L-g-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. g-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. The human g-GCS gene encoding the 367 amino acid catalytic subunit maps to chromosome 6p12. The human g-GCS gene encoding the regulatory subunit maps to chromosome 1p22.1. The two subunits of g-GCS form a heterodimeric zinc metalloprotein that gains activity through formation of a reversible disulfide bond.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant full-length human GCLM protein
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Isotyp
- IgG2a, kappa
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anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 246-274), (C-Term) antibody
GCLM Reaktivität: Human, Maus WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB22980 unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 40-251) antibodyGCLM Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2B8 unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274), (Regulatory Subunit) antibodyGCLM Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) antibodyKD Validated GCLM Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB5535 unconjugated Recombinant Antibody
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 245-274), (C-Term) antibodyGCLM Reaktivität: Human WB, IF, FACS, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (N-Term) antibodyGCLM Reaktivität: Human, Maus, Ratte, Schwein WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 182-231) antibodyGCLM Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Affe, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Schwein, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
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Andere Bezeichnung
- GCLM
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Hintergrund
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Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, GCLM, GCS light chain, GLCLR, Glutamate--cysteine ligase modifier subunit, Glutamate--cysteine ligase regulatory subunit, GSC light chain
Human colon carcinoma (IHC).
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Molekulargewicht
- 31kDa
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Gen-ID
- 2730, 315562
Target
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