Endoglin Antikörper

Produktnummer ABIN7862745

Der Maus Monoklonal anti-Endoglin Antikörper wird verwendet zum Nachweis von Endoglin in Proben von Human, Ratte, Schwein, Pferd und Affe. Er wurde validiert für FACS, ELISA, IF und Func.

Kurzübersicht für Endoglin Antikörper (ABIN7862745)

Target: Endoglin (ENG)

Reaktivität: Human, Ratte, Schwein, Pferd, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Endoglin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Functional Studies (Func)

Klon: ENG-1621

Produktdetails anti-Endoglin Antikörper

Verwendungszweck: Endoglin / CD105 (Angiogenesis Marker) Antibody

Spezifität: CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for Prostate Adenocarcinoma, and cancers of the lung, stomach, breast, and brain.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant extracellular fragment of human Endoglin protein exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8È105ü79oΩC. Antibody without azide - store at -20 to -80È105ü79oΩC. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Endoglin

Target: Endoglin (ENG)

Andere Bezeichnung: Endoglin

Hintergrund:

CD105, END, Endoglin, Eng, HHT1, S-endoglin

A431 or HL-60 cells., HeLa

Molekulargewicht: 80kDa (Monomer), 160kDa (Homodimer)

Gen-ID: 2022, 76753

UniProt: P17813