Rekombinanter EGFRviii Antikörper

Produktnummer ABIN7862726

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch EGFRviii in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter EGFRviii Antikörper (ABIN7862726)

Target: EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser EGFRviii Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: GFR-2600R

Produktdetails anti-EGFRviii Antikörper

Verwendungszweck: Recombinant EGFRvIII (Epidermal Growth Factor Receptor, Variant III) Antibody

Spezifität: EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: KLH conjugate of EGFRvIII-specific, 14-amino acid peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu EGFRviii

Target: EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))

Andere Bezeichnung: EGFRvIII

Hintergrund:

Erbb1 variant III, ERBB1 variant III, HER1 variant III, Proto-oncogene c-ErbB-1 variant III, Receptor Tyrosine Protein Kinase variant III, ErbB1 variant III

A431 cells. Placenta, Breast, Colon or Bladder Carcinoma

Molekulargewicht: ~145kDa (vIII variant)

Gen-ID: 1956, 488293

UniProt: P00533