EGFRviii Antikörper (AA 321-520) (Biotin)

Produktnummer ABIN6943226

Produktdetails anti-EGFRviii Antikörper (Biotin)

Target: EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))

Bindungsspezifität: AA 321-520

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGFRviii Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EGFRvIII

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu EGFRviii

Target: EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))

Andere Bezeichnung: EGFRvIII (EGFRv3 Produkte)

Hintergrund:

Synonyms: GFRvIII, Epidermal growth factor receptor variant type _, epidermal growth factor receptor isoform a variant.

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Gen-ID: 1956

UniProt: P00533