CD21 Antikörper

Produktnummer ABIN7861130

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD21 in IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CD21 Antikörper (ABIN7861130)

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD21 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Klon: CR2-6683

Produktdetails anti-CD21 Antikörper

Verwendungszweck: CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody

Spezifität: Recognizes a protein of 140 kDa, which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: human B cell line SB

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu CD21

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Andere Bezeichnung: CD21

Hintergrund:

CD21, Complement C3d receptor (C3DR), Complement Receptor type 2 (CR2), CVID7, EBV receptor, EBV-R, Epstein-Barr virus receptor, EVBR, SLEB9

Raji or WEHI-231 cells. Tonsil

Molekulargewicht: 140kDa

Gen-ID: 1380, 445757

Pathways: Komplementsystem