Rekombinanter COL2 Antikörper

Produktnummer ABIN7861123

Der Kaninchen Monoklonal anti-COL2 Antikörper (Klon COL2A1-8810R) (ABIN7861123) detektiert spezifisch COL2 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter COL2 Antikörper (ABIN7861123)

Target: COL2 (Collagen, Type II (COL2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser COL2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: COL2A1-8810R

Produktdetails anti-COL2 Antikörper

Verwendungszweck: Recombinant Collagen II (COL2A1) Antibody

Spezifität: The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: bovine collagen type II (CII).

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu COL2

Target: COL2 (Collagen, Type II (COL2))

Andere Bezeichnung: Collagen II

Hintergrund:

Alpha 1 type II collagen, AOM, Cartilage collagen, Chondrocalcin, COL11A3, Collagen II alpha 1 polypeptide, SEDC

Human cartilage|lung or eye.

Molekulargewicht: 190kDa

Gen-ID: 1280, 17441