COL2 Antikörper

Produktnummer ABIN135048

Zitiert in 7+ Publikationen. Der Ziege Polyklonal anti-COL2 Antikörper (ABIN135048) detektiert spezifisch COL2 in WB, ELISA, IP, ICC, IHC (p), IHC (fro) und IEM. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen, Huhn, Rind (Kuh), Schaf und Schwein.

Kurzübersicht für COL2 Antikörper (ABIN135048)

Target: COL2 (Collagen, Type II (COL2))

Reaktivität: Human, Maus, Ratte, Kaninchen, Huhn, Rind (Kuh), Schaf, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser COL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoelectron Microscopy (IEM)

Produktdetails anti-COL2 Antikörper

Verwendungszweck: Goat Anti-Type II Collagen-UNLB

Spezifität: Reacts with conformational determinants on type II collagen Referenced species reactivities include - Human 4,5,10,12,14,18-20,22,24,27,29,31,33,34 Chicken 16,26 Mouse 6,7,15 Porcine 21 Rat 13,17,25 Rabbit 2,9,11,30,32 Bovine 2,3,19,23 Sheep 8,28

Kreuzreaktivität (Details): Exhibits < 10 % cross reactivity with collagen type II, III, IV, V and VI. The antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).

Produktmerkmale: Purified Anti-Type II Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, and immunoprecipitation assays.

Aufreinigung: Purified by affinity chromatography on type II collagen covalently linked to agarose, cross-adsorbed against Collagen types I, III, IV, V, and VI for minimal reactivity

Immunogen: Type II collagen

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Pooled antisera from goats hyperimmunized with type II collagen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: Borate buffered saline, pH 8.2

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Referenzen für anti-COL2 Antikörper (ABIN135048)

Tan Timur, Caron, van den Akker, van der Windt, Visser, van Rhijn, Weinans, Welting, Emans, Jahr: "Increased TGF-β and BMP Levels and Improved Chondrocyte-Specific Marker Expression In Vitro under Cartilage-Specific Physiological Osmolarity." in: International journal of molecular sciences, Vol. 20, Issue 4, (2019) (PubMed).

Kuwahara, Serowoky, Vakhshori, Tripuraneni, Hegde, Lieberman, Crump, Mariani: "Sox9+ messenger cells orchestrate large-scale skeletal regeneration in the mammalian rib." in: eLife, Vol. 8, (2019) (PubMed).

Fujii, Hirota, Yasoda, Takizawa, Morozumi, Nakamura, Yotsumoto, Kondo, Yamashita, Sakane, Kanai, Ueda, Yamauchi, Yamanaka, Nakao, Kuwahara, Jindo, Furuya, Mashimo, Inagaki, Serikawa, Nakao: "Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death." in: PLoS ONE, Vol. 13, Issue 3, pp. e0194812, (2018) (PubMed).

Caron, Emans, Sanen, Surtel, Cremers, Ophelders, van Rhijn, Welting: "The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of ATDC5 Progenitor Cells." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153162, (2016) (PubMed).

Nakao, Osawa, Yasoda, Yamanaka, Fujii, Kondo, Koyama, Kanamoto, Miura, Kuwahara, Akiyama, Bessho, Nakao: "The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth." in: Scientific reports, Vol. 5, pp. 10554, (2016) (PubMed).

van den Akker, Surtel, Cremers, Rodrigues-Pinto, Richardson, Hoyland, van Rhijn, Welting, Voncken: "Novel immortal human cell lines reveal subpopulations in the nucleus pulposus." in: Arthritis research & therapy, Vol. 16, Issue 3, pp. R135, (2014) (PubMed).

Mirmalek-Sani, Orlando, McQuilling, Pareta, Mack, Salvatori, Farney, Stratta, Atala, Opara, Soker: "Porcine pancreas extracellular matrix as a platform for endocrine pancreas bioengineering." in: Biomaterials, Vol. 34, Issue 22, pp. 5488-95, (2013) (PubMed).

Details zu COL2

Target: COL2 (Collagen, Type II (COL2))

Andere Bezeichnung: TypeII Collagen

Hintergrund:

Description: Goat Anti-Type II Collagen-UNLB

NCBI_Official_Symbol: COL2A1

Synoynms: COL2

Gen-ID: 1280

UniProt: P02458