Annexin A2 Antikörper

Produktnummer ABIN7860904

Der Maus Monoklonal anti-Annexin A2 Antikörper (Klon 3D5-4) (ABIN7860904) detektiert spezifisch Annexin A2 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Annexin A2 Antikörper (ABIN7860904)

Target: Annexin A2 (ANXA2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Annexin A2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: 3D5-4

Produktdetails anti-Annexin A2 Antikörper

Verwendungszweck: Annexin A2 Antibody

Spezifität: The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed Calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human Annexin A2 protein

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Annexin A2

Target: Annexin A2 (ANXA2)

Andere Bezeichnung: Annexin A2

Hintergrund:

Annexin A2, Annexin II, heavy chain, ANX2, ANX2L4, arylsulfatase B, CAL1H, calpactin I heavy polypeptide (p36), Calpactin I heavy polypeptide, chromobindin 8, Epididymis secretory protein Li 270, HEL S 270, LIP2, Lipocortin II, LPC2, LPC2D, P36 protein, PAP-IV, Placental anticoagulant protein IV, Protein I

HeLa or A549 cells. Human colon cancer.

Molekulargewicht: 36kDa

Gen-ID: 302, 511605

Pathways: S100 Proteine