Rekombinanter MCM3 Antikörper (AA 650-750)

Produktnummer ABIN7860551

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch MCM3 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter MCM3 Antikörper (AA 650-750) (ABIN7860551)

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MCM3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: MCM3-8972R

Produktdetails anti-MCM3 Antikörper

Bindungsspezifität: AA 650-750

Verwendungszweck: Recombinant MCM3 (Proliferation Marker) Antibody

Spezifität: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (aa 650-750) of human MCM3 protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu MCM3

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Andere Bezeichnung: MCM3

Hintergrund:

Cervical cancer proto-oncogene 5, DNA polymerase alpha holoenzyme-associated protein P1, DNA replication factor MCM3, DNA replication licensing factor mcm3, HCC5, hRlf beta subunit, Human cervical cancer proto oncogene 5, MGC1157, Minichromosome maintenance complex component 3, Minichromosome maintenance deficient 3, P102 protein, Replication licensing factor beta subunit, RLF beta subunit, RLF subunit beta

MCF-7, Jurkat or Ramos cells. Human colon or tonsil.

Molekulargewicht: 115kDa

Gen-ID: 4172, 179565

UniProt: P25205

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA